Association of MOV10L1 gene polymorphisms and male infertility in azoospermic men with complete maturation arrest
نویسندگان
چکیده
منابع مشابه
P-206: Mov10l1 Gene Polymorphisms Are Probably Associated to Male Infertility in Azoospermic Men with Complete Maturation Arrest
Background: Thousands of genes are involved in spermatogenesis. Alterations in any of these genes could lead to male infertility. Moloney leukemia virus 10-Like 1 (Mov10l1) gene is one of the genes that are expressed specifically in germ cells. Genetic disruption of this gene in mouse stops spermatogenesis during Meiosis I and causes azoospermia. Materials and Methods: In this study, the geneti...
متن کاملAssociation of rs737008 in PRM1 and rs4780356 in PRM2 Polymorphisms with Idiopathic Infertility in Iranian men
Aim and Background: Histones are replaced by protamines to package sperm head DNA during mammalian spermatogenesis. Protamine genes variation cause sperm DNA damage and is affect infertility in men. Therefore this study aim was investigation on association of two rs737008 in PRM1 gene and rs4780356 in PRM2 gene polymorphisms with azoospermia and oligospermia in Iranian idiopathic infertile men....
متن کاملP-196: Association rs3819392 Single Nucleotide Polymorphism within The KIT Gene with Azoospermic Male Infertility
Background: Recent studies have shown that KIT is expressed in the cytoplasm of the spermatogonia, acrosomal granules and leydig cells. Reduction in KIT expression in oligozoospermia with an increase in the germ cell apoptosis process. Three single-nucleotide polymorphisms (SNPs) have been identified and these have been studied to discover KIT role in the male infertility. The aim of this study...
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چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولAssociation of Two Polymorphisms in H2B.W Gene with Azoospermia and Severe Oligozoospermia in An Iranian Population
Background During spermatogenesis, the H2B family, member W (H2B.W) gene, encodes a testis specific histone that is co-localized with telomeric sequences and has the potential role to mediate the sperm-specific chromatin remodeling. Previously H2B.W genetic variants were reported to be involved in susceptibility to spermatogenesis impairment. In the present study, two single nucleotide polymorp...
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ژورنال
عنوان ژورنال: Journal of Assisted Reproduction and Genetics
سال: 2014
ISSN: 1058-0468,1573-7330
DOI: 10.1007/s10815-014-0240-1